Bangladesh Fire Kills More Than 100 and Injures Many

Hasan Raza/Associated Press

Firefighters tried to control a fire at a garment factory in Savar, Bangladesh, on Saturday.

MUMBAI — More than 100 people died Saturday and Sunday in a fire at a garment factory outside Dhaka, Bangladesh, in one of the worst industrial tragedies in that country.

It took firefighters more than 17 hours to put out the blaze at the factory, Tazreen Fashions, after it started Saturday evening, a retired fire official said by telephone from Dhaka, Bangladesh’s capital. At least 111 people were killed and scores of workers were taken to hospitals with burns and smoke inhalation injuries.

“The main difficulty was to put out the fire; the sufficient approach road was not there,” said the retired official, Salim Nawaj Bhuiyan, who now runs a fire safety company in Dhaka. “The fire service had to take great trouble to approach the factory.”

Bangladesh’s garment industry, the second largest exporter of clothing after China, has a notoriously poor record of fire safety. Since 2006, more than 500 Bangladeshi workers have died in garment factory fires, according to Clean Clothes Campaign, an anti-sweatshop advocacy group based in Amsterdam. Experts say many of the fires could have been easily avoided if the factories had taken the right precautions. Many factories are in cramped neighborhoods, have too few fire escapes and widely flout safety measures. The industry employs more than three million workers in Bangladesh, mostly women.

Activists say that global clothing brands need to take responsibility for working conditions in Bangladeshi factories that produce the clothes that they sell.

“These brands have known for years that many of the factories they choose to work with are death traps,” Ineke Zeldenrust, the international coordinator for Clean Clothes Campaign, said in a statement. “Their failure to take action amounts to criminal negligence.”

The fire at the Tazreen factory in Savar, northwest of Dhaka, started in a warehouse on the ground floor and quickly spread up the building, which Reuters reported is nine stories high. The two-year-old factory employed about 1,500 workers and had sales of $35 million a year, according to information on the company’s Web site. It made T-shirts, polo shirts and fleece jackets.

Most of the workers who died were on the first and second floors and were killed, fire officials said, because there were not enough exits for them to get out.

“The factory had three staircases, and all of them were down through the ground floor,” said Maj. Mohammad Mahbub, the operations director for the fire department, according to The Associated Press. “So the workers could not come out when the fire engulfed the building.”

In a brief phone call, Delowar Hossain, the managing director of the Tuba Group, the parent company of Tarzeen Fashions, said he was too busy to comment. “Pray for me,” he said and then hung up.

Television news reports showed badly burned bodies lined up on the floor in what appeared to be a government building and showed the injured receiving treatment in hallways of local hospitals. One survivor, Mukta Begum, told Al Jazeera that she and a male colleague escaped by jumping out of a window.

A document posted on the company’s Web site showed that an “ethical sourcing” official for Walmart flagged “violations and/or conditions which were deemed to be high risk” at the factory in May 2011, though it did not specify the nature of the infractions. The notice said that the factory had been given an “orange” grade and that any factories given three such assessments in two years from their last audit would not receive any orders from Walmart for one year.

Bangladesh exports about $18 billion worth of garments and is a big supplier to companies like Walmart, H&M and Tommy Hilfiger. Workers in the country’s factories are among the lowest-paid in the world with entry-level workers making a government-mandated minimum wage of about $37 a month.

Tensions have been running high between workers, who have been demanding an increase in minimum wages, and factory owners and the government. Earlier this year, a union organizer, Aminul Islam, was found tortured and killed outside Dhaka.

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No. 1 Notre Dame beats USC 22-13, earns title shot

LOS ANGELES (AP) — The Fighting Irish punched their ticket to Miami.

Theo Riddick rushed for 146 yards and a touchdown, Kyle Brindza kicked five field goals, and No. 1 Notre Dame secured a spot in the BCS championship game with a 22-13 victory over Southern California on Saturday night.

Everett Golson passed for 217 yards as the Irish (12-0) completed their first perfect regular season since 1988, earning a trip to south Florida on Jan. 7 to play for the storied program's first national title in 24 years.

Although they did little with flash on an electric night at the Coliseum, the Irish woke up more echoes of past Notre Dame greats with a grinding effort in this dynamic intersectional rivalry with USC (7-5), which has lost four of five.

Notre Dame's hard-nosed defense appropriately made the decisive stand in the final minutes, keeping USC out of the end zone on four plays from the Irish 1 with 2:33 to play.

"Well, that's who we are," Notre Dame coach Brian Kelly said. "It's been our defense all year. Our offense is able to manage enough points."

After spending more than a decade looking up at the Trojans, the Irish are back on top of this rivalry with two straight wins in Los Angeles. The school of Knute Rockne, the Four Horsemen and Paul Hornung has new heroes now, from inspirational linebacker Manti Te'o to Kelly, who took the Irish from unranked to start the season to No. 1 in the AP Top 25 for the first time in 19 years.

Te'o, the Heisman Trophy hopeful, had a key interception against USC and became the second Irish defender with three 100-tackle seasons — and he took particular pride in that last defensive stand, which included three straight Trojans runs resulting in nothing.

"It doesn't matter where the ball is," Te'o said. "We're going to protect the end zone at all costs."

After Brindza's school record-tying fifth field goal put the Irish up by nine points with 5:58 left, Marqise Lee caught a 53-yard pass from USC freshman Max Wittek at the Notre Dame 2.

But after USC failed on three straight runs at a defense that has allowed just 11 rushing TDs in 30 games, Wittek threw incomplete to fullback Soma Vainuku, setting off a leaping, chest-bumping celebration on the Notre Dame sideline and in the Irish sections of the sold-out Coliseum.

"They've had a great goal-line defense all year," USC coach Lane Kiffin said. "They've done that to everybody down on the goal line. ... It's just so hard to score touchdowns versus them. When the ball is on the 2-inch line, you'd think you could score touchdowns."

The grind-it-out win highlighted an unforgettable season for the Irish, who began the year with questions about their relevancy and survived some uninspiring performances and nail-biting finishes with their unbeaten record intact.

Notre Dame is likely to face an Southeastern Conference opponent in Miami, but won't know for another week which one. Alabama and Georgia play for the SSEC title in Atlanta.

With the Irish offense repeatedly stalling in the red zone against the Trojans, Brindza went five for six on field goals, even hitting a 52-yarder at the halftime gun.

Wittek passed for 186 yards with two interceptions in his first career start for the Trojans, who completed their tumble from the preseason No. 1 ranking with four losses in five games in an enormously disappointing season. Wittek filled in capably for injured Matt Barkley, but USC is headed to a lower-tier bowl in the first year after its NCAA-mandated two-year postseason ban ended.

Lee caught five passes for 75 yards, yet still broke the Pac-12 single-season receptions record established last year by teammate Robert Woods, who had seven catches for 92 yards.

Barkley watched from the sideline in a grey hoodie with a sling on his right arm after spraining his shoulder in last week's loss at UCLA. The senior and Pac-12 career passing leader won twice in South Bend during his career, but never got to face the Irish at the Coliseum, sidelined by injuries for both visits.

Barkley still ran down the Coliseum tunnel with the rest of the USC seniors for their final home game. He participated in the coin toss, but could only watch while the Irish opened the game with three clock-consuming drives resulting in 13 points.

USC's much-criticized defensive caution under assistant head coach Monte Kiffin was exploited by the Irish, with Golson patiently finding the sags in the Trojans' pass coverage for 181 yards passing in the first half. Riddick went 9 yards for a TD in the first quarter, but USC also stiffened to hold Notre Dame to field goals twice in the red zone.

Notre Dame held its 12th straight opponent without a first-quarter touchdown, but Wittek found Woods for a 9-yard score on the first play of the second quarter — just the ninth touchdown allowed by Notre Dame all season long. The Irish took a 16-10 lead to halftime when Brindza hit the second-longest field goal in Notre Dame history.

Te'o made the seventh interception of his phenomenal season when Wittek threw directly to him on USC's second play of the second half. Both teams struggled to move the ball in the third quarter, and USC settled for a field goal with 9:20 to play just a few moments after Kiffin called a timeout right before a play that ended with Lee appearing to catch a pass on the goal line.

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Protests Erupt After Egypt’s Leader Seizes New Power

Tara Todras-Whitehill for The New York Times

Egyptians in central Cairo ran from tear gas during clashes with the police on Friday. Protesters took to the streets in several cities. More Photos »

CAIRO — Protests erupted across Egypt on Friday, as opponents of President Mohamed Morsi clashed with his supporters over a presidential edict that gave him unchecked authority and polarized an already divided nation while raising a specter, the president’s critics charged, of a return to autocracy.  

In an echo of the uprising 22 months ago, thousands of protesters chanted for the downfall of Mr. Morsi’s government in Cairo, while others ransacked the offices of the president’s former party in Suez, Alexandria and other cities.

Mr. Morsi spoke to his supporters in front of the presidential palace here, imploring the public to trust his intentions as he cast himself as a protector of the revolution and a fledgling democracy.

In a speech that was by turns defensive and conciliatory, he ultimately gave no ground to the critics who now were describing him as a pharaoh, in another echo of the insult once reserved for the deposed president, Hosni Mubarak.

“God’s will and elections made me the captain of this ship,” Mr. Morsi said.

The battles that raged on Friday — over power, legitimacy and the mantle of the revolution — posed a sharp challenge not only to Mr. Morsi but also to his opponents, members of secular, leftist and liberal groups whose crippling divisions have stifled their agenda and left them unable to confront the more popular Islamist movement led by the Muslim Brotherhood.

The crisis over his power grab came just days after the Islamist leader won international praise for his pragmatism, including from the United States, for brokering a cease-fire between Hamas and Israel.

On Friday, the State Department expressed muted concern over Mr. Morsi’s decision. “One of the aspirations of the revolution was to ensure that power would not be overly concentrated in the hands of any one person or institution,” said the State Department spokeswoman, Victoria Nuland.

She said, “The current constitutional vacuum in Egypt can only be resolved by the adoption of a constitution that includes checks and balances, and respects fundamental freedoms, individual rights and the rule of law consistent with Egypt’s international commitments.”

But the White House was notably silent after it had earlier this week extolled the emerging relationship between President Obama and Mr. Morsi and credited a series of telephone calls between the two men with helping to mediate the cease-fire in Gaza.

For Mr. Morsi, who seemed to be saying to the nation that it needed to surrender the last checks on his power in order to save democracy from Mubarak-era judges, the challenge was to convince Egyptians that the ends justified his means.

But even as he tried, thousands of protesters marched to condemn his decision. Clashes broke out between the president’s supporters and his critics, and near Tahrir Square, the riot police fired tear gas and bird shot as protesters hurled stones and set fires.

Since Thursday, when Mr. Morsi issued the decree, the president and his supporters have argued that he acted precisely to gain the power to address the complaints of his critics, including the families of protesters killed during the uprising and its aftermath.

By placing his decisions above judicial review, the decree enabled him to replace a public prosecutor who had failed to win convictions against senior officers implicated in the killings of protesters.

The president and his supporters also argued that the decree insulated the Constituent Assembly, which is drafting the constitution, from meddling by Mubarak-era judges.

Since Mr. Mubarak’s ouster, courts have dissolved Parliament, kept a Mubarak loyalist as top prosecutor and disbanded the first Assembly.

But by ending legal appeals, the decree also removed a safety valve for critics who say the Islamist majority is dominating the drafting of the constitution.

Mayy El Sheikh contributed reporting from Cairo, and Helene Cooper from Washington.

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Ex-boxer 'Macho' Camacho dies after shooting

SAN JUAN, Puerto Rico (AP) — Hector "Macho" Camacho, a Puerto Rican boxer known for skill and flamboyance in the ring as well as for a messy personal life and run-ins with the police, was declared dead on Saturday, four days after being shot in the face. He was 50.

Shot while sitting in a parked car outside a bar Tuesday with a friend in the city of Bayamon, he was declared dead at the Centro Medico trauma center in San Juan. The friend, 49-year-old Adrian Mojica Moreno, died at the scene of the shooting. Police said Mojica had nine small bags of cocaine in his pocket and a 10th bag was found open in the car.

Originally from Bayamon, just outside San Juan, Camacho was long regarded as a flashy if volatile talent, a skilled boxer who was perhaps overshadowed by his longtime foil, Mexican superstar Julio Cesar Chavez, who would beat him in a long-awaited showdown in Las Vegas in 1992.

Camacho fought professionally for three decades, from his humble debut against David Brown at New York's Felt Forum in 1980 to an equally forgettable swansong against Sal Duran in Kissimmee, Florida, in 2010.

In between, he fought some of the biggest stars spanning two eras, including Sugar Ray Leonard, Felix Trinidad, Oscar De La Hoya and Roberto Duran.

"This is something I've done all my life, you know?" Camacho told The Associated Press after a workout in 2010. "A couple years back, when I was doing it, I was still enjoying it. The competition, to see myself perform. I know I'm at the age that some people can't do this no more."

Camacho's family moved to New York when he was young and he grew up in Spanish Harlem, which at the time was rife with crime. Camacho landed in jail as a teenager before turning to boxing, which for many kids in his neighborhood provided an outlet for their aggression.

Former featherweight champion Juan Laporte, a friend since childhood, described Camacho as "like a little brother who was always getting into trouble," but otherwise combined a friendly nature with a powerful jab.

"He's a good human being, a good hearted person," Laporte said as he waited with other friends and members of the boxer's family outside the hospital in San Juan after the shooting. "A lot of people think of him as a cocky person but that was his motto ... inside he was just a kid looking for something."

Laporte lamented that Camacho never found a mentor outside the boxing ring.

"The people around him didn't have the guts or strength to lead him in the right direction," Laporte said. "There was no one strong enough to put a hand on his shoulder and tell him how to do it."

Drug, alcohol and other problems trailed Camacho after the prime of his boxing career. He was sentenced in 2007 to seven years in prison for the burglary of a computer store in Mississippi. While arresting him on the burglary charge in January 2005, police also found the drug ecstasy.

A judge eventually suspended all but one year of the sentence and gave Camacho probation. He wound up serving two weeks in jail, though, after violating that probation.

Camacho's former wife, Amy, obtained a restraining order against him in 1998, alleging he threatened her and one of their children. The couple, who had two children at the time, later divorced.

He divided his time between Puerto Rico and Florida in recent years, appearing on Spanish-language television as well as on a reality show called "Es Macho Time!" on YouTube.

Inside the boxing ring, Camacho flourished. He won three Golden Gloves titles as an amateur, and after turning pro, he quickly became a contender with an all-action style reminiscent of other Puerto Rican fighters.

Long promoted by Don King, Camacho won his first world title by beating Rafael Limon in a super-featherweight bout in Puerto Rico on Aug. 7, 1983. He moved up in weight two years later to capture a lightweight title by defeating Jose Luis Ramirez, and successfully defended the belt against fellow countryman Edwin Rosario.

The Rosario fight, in which the victorious Camacho still took a savage beating, persuaded him to scale back his ultra-aggressive style in favor of a more cerebral, defensive approach.

The change in style was a big reason that Camacho, at the time 38-0, lost a close split decision to Greg Haugen at Caesar's Palace in Las Vegas in 1991.

Camacho won the rematch to set up his signature fight against Chavez, this time at the Thomas & Mack Center in Las Vegas. Camacho was roundly criticized for his lack of action, and the Mexican champion won a lopsided unanimous decision to retain the lightweight title.

It was at that point that Camacho became the name opponent for other rising contenders, rather than the headliner fighting for his own glory.

He lost a unanimous decision to another young Puerto Rican fighter, Trinidad, and was soundly defeated by De La Hoya. In 1997, Camacho ended Leonard's final comeback with a fifth-round knockout. It was Camacho's last big victory even though he boxed for another decade.

"Hector was a fighter who brought a lot of excitement to boxing," said Ed Brophy, executive director of International the Boxing Hall of Fame. "He was a good champion. Roberto Duran is kind of in a class of his own, but Hector surely was an exciting fighter that gave his all to the sport."

The fighter's last title bout came in 1997 against welterweight champion Oscar De La Hoya, who won by unanimous decision. Camacho's last fight was his defeat by Duran in May 2010. He had a career record of 79-6-3.

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Scientists See Advances in Deep Learning, a Part of Artificial Intelligence

Hao Zhang/The New York Times

A voice recognition program translated a speech given by Richard F. Rashid, Microsoft’s top scientist, into Mandarin Chinese.

Using an artificial intelligence technique inspired by theories about how the brain recognizes patterns, technology companies are reporting startling gains in fields as diverse as computer vision, speech recognition and the identification of promising new molecules for designing drugs.

The advances have led to widespread enthusiasm among researchers who design software to perform human activities like seeing, listening and thinking. They offer the promise of machines that converse with humans and perform tasks like driving cars and working in factories, raising the specter of automated robots that could replace human workers.

The technology, called deep learning, has already been put to use in services like Apple’s Siri virtual personal assistant, which is based on Nuance Communications’ speech recognition service, and in Google’s Street View, which uses machine vision to identify specific addresses.

But what is new in recent months is the growing speed and accuracy of deep-learning programs, often called artificial neural networks or just “neural nets” for their resemblance to the neural connections in the brain.

“There has been a number of stunning new results with deep-learning methods,” said Yann LeCun, a computer scientist at New York University who did pioneering research in handwriting recognition at Bell Laboratories. “The kind of jump we are seeing in the accuracy of these systems is very rare indeed.”

Artificial intelligence researchers are acutely aware of the dangers of being overly optimistic. Their field has long been plagued by outbursts of misplaced enthusiasm followed by equally striking declines.

In the 1960s, some computer scientists believed that a workable artificial intelligence system was just 10 years away. In the 1980s, a wave of commercial start-ups collapsed, leading to what some people called the “A.I. winter.”

But recent achievements have impressed a wide spectrum of computer experts. In October, for example, a team of graduate students studying with the University of Toronto computer scientist Geoffrey E. Hinton won the top prize in a contest sponsored by Merck to design software to help find molecules that might lead to new drugs.

From a data set describing the chemical structure of 15 different molecules, they used deep-learning software to determine which molecule was most likely to be an effective drug agent.

The achievement was particularly impressive because the team decided to enter the contest at the last minute and designed its software with no specific knowledge about how the molecules bind to their targets. The students were also working with a relatively small set of data; neural nets typically perform well only with very large ones.

“This is a really breathtaking result because it is the first time that deep learning won, and more significantly it won on a data set that it wouldn’t have been expected to win at,” said Anthony Goldbloom, chief executive and founder of Kaggle, a company that organizes data science competitions, including the Merck contest.

Advances in pattern recognition hold implications not just for drug development but for an array of applications, including marketing and law enforcement. With greater accuracy, for example, marketers can comb large databases of consumer behavior to get more precise information on buying habits. And improvements in facial recognition are likely to make surveillance technology cheaper and more commonplace.

Artificial neural networks, an idea going back to the 1950s, seek to mimic the way the brain absorbs information and learns from it. In recent decades, Dr. Hinton, 64 (a great-great-grandson of the 19th-century mathematician George Boole, whose work in logic is the foundation for modern digital computers), has pioneered powerful new techniques for helping the artificial networks recognize patterns.

Modern artificial neural networks are composed of an array of software components, divided into inputs, hidden layers and outputs. The arrays can be “trained” by repeated exposures to recognize patterns like images or sounds.

These techniques, aided by the growing speed and power of modern computers, have led to rapid improvements in speech recognition, drug discovery and computer vision.

Deep-learning systems have recently outperformed humans in certain limited recognition tests.

Last year, for example, a program created by scientists at the Swiss A. I. Lab at the University of Lugano won a pattern recognition contest by outperforming both competing software systems and a human expert in identifying images in a database of German traffic signs.

The winning program accurately identified 99.46 percent of the images in a set of 50,000; the top score in a group of 32 human participants was 99.22 percent, and the average for the humans was 98.84 percent.

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New Zealand Wants a Hollywood Put on Its Map

WELLINGTON, New Zealand — Standing by his desk in New Zealand’s distinctive round Parliament building, known locally as the Beehive, Prime Minister John Key proudly brandished an ornately engraved sword. It was used, he said, by Frodo Baggins, the protagonist of the “Lord of the Rings” trilogy, and in the films it possesses magical powers that cause it to glow blue in the presence of goblins.

“This was given to me by the president of the United States,” said Mr. Key, marveling that President Obama’s official gift to New Zealand was, after all, a New Zealand product.

In Mr. Key’s spare blond-wood office — with no goblins in sight — the sword looked decidedly unmagical. But it served as a reminder that in New Zealand, the business of running a country goes hand in hand with the business of making movies.

For better or worse, Mr. Key’s government has taken extreme measures that have linked its fortunes to some of Hollywood’s biggest pictures, making this country of 4.4 million people, slightly more than the city of Los Angeles, a grand experiment in the fusion of film and government.

That union has been on enthusiastic display here in recent weeks as “The Hobbit: An Unexpected Journey,” the first of three related movies by the director Peter Jackson, approached its world premiere on Wednesday in Wellington (and on Dec. 14 in the United States). Anticipation in New Zealand has been building, and there are signs everywhere of the film’s integration into Kiwi life — from the giant replica of the movie’s Gollum creature suspended over the waiting area at Wellington Airport to the gift shops that are expanding to meet anticipated demand for Hobbit merchandise (elf ears, $14).

But the path to this moment has been filled with controversy. Two years ago, when a dispute with unions threatened to derail the “Hobbit” movies — endangering several thousand jobs and a commitment of some $500 million by Warner Brothers — Mr. Key persuaded the Parliament to rewrite its national labor laws.

It was a breathtaking solution, even in a world accustomed to generous public support of movie projects, and a substantial incentive package was included: the government agreed to contribute $99 million in production costs and add $10 million to the studio’s marketing budget. And its tourism office will spend about $8 million in its current fiscal year, and probably more in the future, as part of a promotional campaign with Time Warner that is marketing the country as a film-friendly fantasyland.

For a tiny nation like New Zealand, where plans to cut $35 million from the education budget set off national outrage earlier this year (and a backtrack from the government), the “Hobbit” concessions were difficult for many to swallow, especially since the country had already provided some $150 million in support for the three “Lord of the Rings” movies.

Now, even amid the excitement of the “Hobbit” opening, skepticism about the government’s film-centric strategy remains. And recently it has become entangled with new suspicions: that Mr. Key’s government is taking cues from America’s powerful film industry in handling a request by United States officials for the extradition of Kim Dotcom, the mogul whose given name was Kim Schmitz, so he can face charges of pirating copyrighted material.

New Zealand’s political scene erupted in September, as Mr. Key publicly apologized to Mr. Dotcom for what turned out to be illegal spying on him by the country’s Government Communications Security Bureau. The Waikato Times, a provincial paper, taunted Mr. Key, accusing him of making New Zealand the “51st state,” while others suggested that a whirlwind trip by Mr. Key to Los Angeles in early October was somehow tied to the Dotcom case.

“No studio executive raised it with me,” Mr. Key said in an interview last month. He spoke the day after a private dinner where he lobbied executives from Disney, Warner Brothers, Fox and other companies for still more New Zealand film work, with Mr. Jackson, a New Zealander, joining by video link.

Mr. Key has been sharply criticized for cozying up to Mr. Jackson in what some consider unseemly ways. Last year, a month before elections in which he and his National Party were fighting to keep control of the government, Mr. Key skipped an appointment with Queen Elizabeth II in Australia to visit the Hobbiton set. He also interviewed Mr. Jackson on a radio show, prompting an outcry from the opposition.

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Military Analysis: For Israel, Gaza Conflict Is Test for an Iran Confrontation

Menahem Kahana/Agence France-Presse — Getty Images

An Israeli missile is launched from a battery. Officials said their antimissile system shot down 88 percent of all assigned targets.

WASHINGTON — The conflict that ended, for now, in a cease-fire between Hamas and Israel seemed like the latest episode in a periodic showdown. But there was a second, strategic agenda unfolding, according to American and Israeli officials: The exchange was something of a practice run for any future armed confrontation with Iran, featuring improved rockets that can reach Jerusalem and new antimissile systems to counter them.

It is Iran, of course, that most preoccupies Prime Minister Benjamin Netanyahu and President Obama. While disagreeing on tactics, both have made it clear that time is short, probably measured in months, to resolve the standoff over Iran’s nuclear program.

And one key to their war-gaming has been cutting off Iran’s ability to slip next-generation missiles into the Gaza Strip or Lebanon, where they could be launched by Iran’s surrogates, Hamas, Hezbollah and Islamic Jihad, during any crisis over sanctions or an Israeli strike on Iran’s nuclear facilities.

Michael B. Oren, the Israeli ambassador to the United States and a military historian, likened the insertion of Iranian missiles into Gaza to the Cuban missile crisis.

“In the Cuban missile crisis, the U.S. was not confronting Cuba, but rather the Soviet Union,” Mr. Oren said Wednesday, as the cease-fire was declared. “In Operation Pillar of Defense,” the name the Israel Defense Force gave the Gaza operation, “Israel was not confronting Gaza, but Iran.”

It is an imprecise analogy. What the Soviet Union was slipping into Cuba 50 years ago was a nuclear arsenal. In Gaza, the rockets and parts that came from Iran were conventional, and, as the Israelis learned, still have significant accuracy problems. But from one point of view, Israel was using the Gaza battle to learn the capabilities of Hamas and Islamic Jihad — the group that has the closest ties to Iran — as well as to disrupt those links.

Indeed, the first strike in the eight-day conflict between Hamas and Israel arguably took place nearly a month before the fighting began — in Khartoum, the capital of Sudan, as another mysterious explosion in the shadow war with Iran.

A factory said to be producing light arms blew up in spectacular fashion on Oct. 22, and within two days the Sudanese charged that it had been hit by four Israeli warplanes that easily penetrated the country’s airspace. Israelis will not talk about it. But Israeli and American officials maintain that Sudan has long been a prime transit point for smuggling Iranian Fajr rockets, the kind that Hamas launched against Tel Aviv and Jerusalem over recent days.

The missile defense campaign that ensued over Israeli territory is being described as the most intense yet in real combat anywhere — and as having the potential to change warfare in the same way that novel applications of air power in the Spanish Civil War shaped combat in the skies ever since.

Of course, a conflict with Iran, if a last-ditch effort to restart negotiations fails, would look different than what has just occurred. Just weeks before the outbreak in Gaza, the United States and European and Persian Gulf Arab allies were practicing at sea, working on clearing mines that might be dropped in shipping lanes in the Strait of Hormuz.

But in the Israeli and American contingency planning, Israel would face three tiers of threat in a conflict with Iran: the short-range missiles that have been lobbed in this campaign, medium-range rockets fielded by Hezbollah in Lebanon and long-range missiles from Iran.

The last of those three could include the Shahab-3, the missile Israeli and American intelligence believe could someday be fitted with a nuclear weapon if Iran ever succeeded in developing one and — the harder task — shrinking it to fit a warhead.

A United States Army air defense officer said that the American and Israeli militaries were “absolutely learning a lot” from this campaign that may contribute to a more effective “integration of all those tiered systems into a layered approach.”

The goal, and the challenge, is to link short-, medium- and long-range missile defense radar systems and interceptors against the different types of threats that may emerge in the next conflict.

Even so, a historic battle of missile versus missile defense has played out in the skies over Israel, with Israeli officials saying their Iron Dome system shot down 350 incoming rockets — 88 percent of all targets assigned to the missile defense interceptors. Israeli officials declined to specify the number of interceptors on hand to reload their missile-defense batteries.

Before the conflict began, Hamas was estimated to have amassed an arsenal of 10,000 to 12,000 rockets. Israeli officials say their pre-emptive strikes on Hamas rocket depots severely reduced the arsenal of missiles, both those provided by Iran and some built in Gaza on a Syrian design.

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Patriots roll past Jets 49-19 with big 2nd quarter

EAST RUTHERFORD, N.J. (AP) — Tom Brady couldn't believe what happened. Neither could Bill Belichick, nor the rest of the New England Patriots, for that matter.

They were up 7-0 on the New York Jets one minute, and 28-0 the next. Literally.

Three touchdowns in 52 seconds. That was all it took to send the high-scoring Patriots to a 49-19 victory Thursday night — and put the bumbling Jets on the verge of seeing their season slip away.

"It all happened so fast," Patriots linebacker Jerod Mayo said. "I've never been part of anything like that, but I'm glad that we were on the right side of it."

Brady threw three touchdown passes and ran for a score as the Patriots (8-3) took advantage of five turnovers and used a 35-point second quarter — including the three TDs in less than a minute — to cruise past the Jets (4-7).

"That was quick," Patriots defensive end Rob Ninkovich said. "They were some of the quickest scores I've ever seen on any level."

New England's 35 second-quarter points tied for the fourth-most in a quarter in NFL history. After a scoreless opening period, the Patriots then went on a touchdown spree despite holding the ball for only 2:14 as the Jets kept giving the ball away.

"I was unfortunately on the other side of that in a Pro Bowl where they scored on a fumble, then an interception," Belichick said. "It doesn't take a lot to score like that — defensive touchdowns, special teams, they can add up in a hurry.

"Nothing surprises me in the NFL."

The Patriots jumped on a poor decision by Mark Sanchez, who ruined a nice drive by keying in on Jeremy Kerley on second-and-6 from the 23. Steve Gregory read the play the whole way for an easy interception.

Brady then led the Patriots on a 15-play, 84-yard drive that was capped by Wes Welker's 3-yard touchdown catch on the first play of the second quarter.

Things got out of hand in a hurry a few minutes later.

After New England recovered a fumble by Shonn Greene, Brady threw a swing pass on first down to Shane Vereen, who zipped down the left sideline untouched for an 83-yard touchdown that made it 14-0 with 9:43 remaining in the opening half.

The Patriots were back in the end zone moments later after Sanchez fumbled on second down as he fell when he slammed into right guard Brandon Moore's backside. Gregory picked up the ball and ran it 32 yards for a score to put New England up 21-0 with 9 minutes left.

And, the Patriots weren't done.

Joe McKnight, one of the league's top returners, fumbled the ensuing kickoff on a hit by Devin McCourty. Julian Edelman grabbed the ball out of the air and scooted 22 yards for yet another score, making it 28-0 with 8:51 remaining in the half.

"That was crazy," Sanchez said. "I've never seen anything like that. This is a team you can't turn the ball over against because they make you pay. That was a great display of that today."

Disgusted Jets fans were chanting for Tim Tebow to play before the second quarter of this Thanksgiving showdown was over, and booing as the team left the MetLife Stadium field at halftime.

"Shoot, I don't blame them for booing," Jets coach Rex Ryan said.

New England, which beat Indianapolis 59-24 on Sunday, scored four touchdowns in just over 6 minutes, helping Belichick become the eighth coach in NFL history with 200 career victories, including the playoffs.

"There's no coach I'd ever want to play for than him," Brady said.

Edelman also caught a 56-yard pass for a score before leaving with a head injury, and Stevan Ridley ran for a touchdown as New England set a franchise record with 108 points in a two-game stretch.

The Patriots improved to 19-0 in the second half of the season since 2010. They were 8-0 that year and last year, and are 3-0 this season after the midway point.

Meanwhile, the Jets allowed their most points since giving up 52 to Miami in the 1995 season opener, and will likely have to win their remaining five games to even have an outside chance at the postseason.

"Discouraged? Of course," Ryan said. "I'll put it to you this way: We're about as wounded as you possibly can be, but we're not dead."

New England was without star tight end Rob Gronkowski, out a few weeks after breaking his left forearm against Indianapolis. It didn't need him — not with the Jets fumbling and stumbling around.

Brady finished 18 of 28 for 323 yards before leaving with 2 minutes left in the game. He reached 3,000 yards passing for the 10th time, becoming one of six players to accomplish the feat. He also passed Dan Fouts for 10th place on the career passing list.

Tight end Aaron Hernandez returned after missing three games with a sprained ankle and had two catches for 36 yards.

Sanchez was 26 of 36 for 301 yards with a touchdown and an interception. Tebow didn't play at all — revealing after the game that he has two broken ribs — and stood on the sideline with a cap on throughout despite the occasional chants for him to get some snaps.

It looked as though this one might be a close as both teams missed opportunities to score in the opening quarter, including Stephen Gostkowski going wide left on a 39-yard field goal attempt for New England. The Jets were hoping to boost their playoff hopes and keep some momentum going after a 27-13 victory at St. Louis on Sunday that snapped a three-game skid.

The Patriots had other plans, sweeping their AFC East rivals for the second straight season.

"We did a good job," Vereen said, "of putting the hammer down when they were down."

NOTES: Edelman left the game early in the third quarter on a helmet-to-helmet hit by LaRon Landry on an end-around during which he fumbled. Belichick would say only "we'll see," when asked about the injury. ... Jets WR Clyde Gates also left with a head injury in the second quarter after a hard hit from Kyle Arrington. ... Jets WR Chaz Schilens didn't speak to the media after the game, saying he had also suffered a head injury. ... Ridley was called for a chop block in the end zone midway through the third quarter, giving the Jets a safety.

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Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL

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Documents Show F.D.A.’s Failures in Meningitis Outbreak

Newly released documents add vivid detail to the emerging portrait of the Food and Drug Administration’s ineffective and halting efforts to regulate a Massachusetts company implicated in a national meningitis outbreak that has sickened nearly 500 people and killed 34.

In the documents, released on Tuesday in response to a Freedom of Information Act request, the agency would threaten to bring the full force of its authority down on the company, only to back away, citing lack of jurisdiction.

The company, the New England Compounding Center, at times cooperated with F.D.A. inspectors and promised to improve its procedures, and at other times challenged the agency’s legal authority to regulate it, refused to provide records and continued to ship a drug in defiance of the agency’s concerns.

Some of the documents were summarized last week by Congressional committees that held hearings on the meningitis outbreak. Republicans and Democrats criticized the F.D.A. for failing to act on information about unsafe practices at the company as far back as March 2002.

By law, compounding pharmacies are regulated primarily by the states, but the pharmacies have grown over the years into major suppliers of some of the country’s biggest hospitals. The F.D.A. is asking Congress for stronger, clearer authority to police them, but Republicans have said the agency already has enough power.

Records show that the agency was sometimes slow in pursuing its own inspection findings. In one case involving the labeling and marketing of drugs, the agency issued a warning letter to New England Compounding 684 days after an inspection, a delay that the company’s chief pharmacist complained was so long that some of the letter’s assertions no longer applied to its operations.

The agency said in a statement Wednesday that it “was not the timeline we strive for,” but that much of the delay was because of “our limited, unclear and contested authority in this area.” Because of litigation, it said, there was “significant internal discussion about how to regulate compounders.”

The agency first inspected the company in April 2002 after reports that two patients had become dizzy and short of breath after being injected with a steroid made by the company.

 On the first day of the inspection, Barry Cadden, the chief pharmacist, was cooperative, but the next day, the agency inspectors wrote, Mr. Cadden “had a complete change in attitude & basically would not provide any additional information either by responding to questions or providing records,” adding that he challenged their legal authority to be at his pharmacy at all.

The F.D.A. was back at New England Compounding in October 2002 because of possible contamination of another of its products, methylprednisolone acetate, the same drug involved in the current meningitis outbreak.

 While the F.D.A. had the right to seize an adulterated steroid, officials at the time said that action alone would not resolve the company’s poor compounding practices. In a meeting with Massachusetts regulators, F.D.A. officials left authority in the hands of the state, which “would be in a better position to gain compliance or take regulatory action,” according to a memo by an F.D.A. official summarizing the meeting.

 David Elder, compliance branch director for the F.D.A.’s New England District, warned at the meeting that there was the “potential for serious public health consequences if N.E.C.C.’s compounding practices, in particular those relating to sterile products, are not improved.”

 The company fought back hard, repeatedly questioning the F.D.A.’s jurisdiction. In a September 2004 inspection over concerns that the company was dispensing trypan blue, a dye used for some eye surgeries that had not been approved by the F.D.A., Mr. Cadden told the agency inspector that he had none in stock.

But in the clean room, the inspector noticed a drawer labeled “Trypan Blue,” which contained 189 vials of the medicine.

A few days later, Mr. Cadden was defiant. He told the agency that he was continuing to dispense trypan blue and that there was nothing in the law saying a compounder could not dispense unapproved products.

 The conversation turned testy. “Don’t answer any more questions!” Mr. Cadden told another pharmacy executive, according to the F.D.A.’s report.

Mr. Cadden rejected many of the assertions in the warning letter that finally came in December 2006. The next correspondence from the agency did not come until almost two years later, in October 2008, saying that the agency still had “serious concerns” about the company’s practices, and that failing to correct them could result in seizure of products and an injunction against the company and its principals.

It is not known whether any corrective actions were taken. The agency did not conduct another inspection until the recent meningitis outbreak.

Denise Grady contributed reporting.

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The Lede Blog: Vignettes of Black Friday

With promotions, discounts and doorbusters already well under way on Thanksgiving Day itself, many big-box retailers are making Black Friday stretch longer than ever. The Lede is checking out the mood of American consumers in occasional vignettes Thursday and Friday as the economically critical holiday shopping season kicks off.

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